Weekly Link Round-Up: Veterans Twice as Likely to Suffer ALS, 2 Reasons to Be Optimistic About Biogen’s Alzheimer’s Drug & What’s Stopping Men from Filling the Caregiver Shortage?

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ALS

Diseases Like ALS Common Cause of Death for Former Soccer Players, Scottish Study Finds:

A Scottish study found that athletes who played professional football (Soccer) are three times more likely to die of a neurodegenerative disease than the average person. There is a growing awareness about the potential association between contacts spots like American football and soccer, and the risk of neurodegenerative disease later. After the age of 70, the mortality rates of these former athletes surpassed the general population. The mortality rate for those players with such conditions was 5.07 times higher form Alzheimer’s, Motor Neuron Diseases (like ALS) were 4.33 times hirer, and finally, Parkinson’s disease was 2.15 times higher. 

 

Read More: https://alsnewstoday.com/2020/01/24/neurodegerative-diseases-common-killer-of-former-soccer-players-scottish-study/

 

Research Shows Veterans Twice as Likely to Suffer ALS

Research has shown that U.S. military veterans are twice as likely to suffer from ALS as the general public. Doctors and scientists believe that it may be environmental factors such as exposure to oil wells and burning fumes. These increased diagnoses have included veterans from a variety of conflicts, including those in the Persian Gulf War, the Korean War, World War II, and the Vietnam War. Many are pushing for veterans diagnosed with ALS to contact the VA and get enrolled in clinical trials of new ALS treatments. 

Read More: https://www.news4jax.com/health/2020/01/24/research-shows-veterans-twice-as-likely-to-suffer-als/

 

Single Injection of RNA Therapy Blocks Degeneration, Prevents Disease Progression in Mice Models of Familial ALS: 

The treatment is done through a virus-delivered gene-silencer targeting the SOD1 gene. Research suggests the mutations in the SOD1 gene is one of the most frequent causes of familial ALS. If the treatment is given before the onset of symptoms resulted in near-complete preservation of spinal neurons and muscle innervation. The treatment also blocked disease progression in mice already showing ALS-like symptoms. 

 

Read More: https://alsnewstoday.com/2020/01/22/single-injection-of-rna-therapy-blocks-degeneration-prevents-disease-progression-in-mice-models-of-familial-als/

 

Alzheimer’s/Dementia

Monty Python star Terry Jones Dies at 77:

Terry Jones who was a founding member of Monty Python died at age 77 after suffering from dementia. "We have all lost a kind, funny, warm, creative and truly loving man whose uncompromising individuality, relentless intellect and extraordinary humor has given pleasure to countless millions across six decades," Jones's wife, Anna Soderstrom, and children Bill, Sally and Siri, said in a statement. Terry was still good-humored though his battle with a rare form of dementia. In 2014, more than three decades after their last live performance, the five surviving Pythons reunited for a string of stage shows that revived their old skits for adoring audiences.

Palin would recall that during the stage run, Jones struggled for the first time with remembering lines. Two years later, Jones's family announced that he had been diagnosed with frontotemporal dementia, which gradually robbed him of the ability to write and speak.

 

Read More: https://www.pbs.org/newshour/arts/monty-python-star-terry-jones-dies-at-77

2 Reasons to be Optimistic About Biogen’s Alzheimer’s Drug

Biogen said the earlier data, which didn't meet endpoints and resulted in halting trials, involved giving the drug at lower doses. In patients with a gene variant that increases a side effect risk, researchers started with lower doses, then later increased them when it was deemed safe to do so. Therefore, that study, called Engage, had fewer participants getting high doses for the full treatment period compared with Emerge, the second study. In Emerge, the high dose of aducanumab reduced clinical decline, while in Engage, only the subset of patients given high doses showed the same result. The two reasons to be optimistic is the FDA has been approving more and more drugs and the Alzheimer’s drug is a treatment for a currently unmet need. 

 

Read More: https://www.fool.com/investing/2020/01/21/2-reasons-to-be-optimistic-about-biogens-alzheimer.aspx

 

Caregiver

There’s A Caregiver Shortage- What’s Stopping Men From Filling The Gap?

Despite a growing number of men who are not working and a growing number of direct support jobs that need filling, few men are joining the profession. There are two big factors keeping men out of the field, they don't feel capable and they don't feel valued. Men are very capable of being very compassionate and competent caregivers, it’s just that our society doesn’t socialize them to think of themselves in that way, and it also doesn’t reward people for doing that kind of work, so there isn’t a lot of motivation for men to learn how to be good caregivers. But absolutely, they can be.

 

Read More: https://www.wxxinews.org/post/theres-caregiver-shortage-whats-stopping-men-filling-gap

 

Stroke

Stroke: Not Your Grandfather’s Disease Anymore:

Strokes are typically associated with older adults. It may be more common in people over 75 but younger people are not exempt and their numbers appear to be rising. The risk factors in these younger age groups are the same as their older counterparts; high blood pressure, smoking, diabetes and more. According to the CDC Obesity is what is taking a toll on the young and increasing their likelihood of a stroke. 

 

Read More: https://www.baystatebanner.com/2020/01/24/stroke-not-your-grandfathers-disease-anymore/

 

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