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AMX0035 Significantly Slows Disease Progression in ALS, Phase 2 Study Shows:
This article covers the recent CENTAUR Phase 2 trial of AMX035. The study showed significantly slowed progression of amyotrophic lateral sclerosis in patients who took it compared to those who were administered a placebo. The study covered scores of speech, swallowing, dressing, hygiene, and other daily functions, these numbers declined much more slowly than the placebo group over the trial’s 24 week period. AMX0035 is a combination therapy that acts to prevent nerve cell death by blocking stress signals within the mitochondria and endoplasmic reticulum. Unlike others in developing treatments for ALS, AMX0035 does not target the root causes but instead aims to preserve the motor neurons that are lost in ALS patients. The research will continue on AMX0035 as researchers work toward developing new treatments for ALS.
Alzheimers & Dementia:
Scientists Reach Out To Minority Communities To Diversify Alzheimer’s Studies:
Black and Hispanic Americans are especially vulnerable to Alzheimer’s disease. Yet they’re often underrepresented in scientific studies of the disease. African Americans are twice as likely as white Americans to develop Alzheimer’s. There is a national effort funded by the National Institute on Aging to expand and diversify participation in Alzheimer’s studies. Previous research has shown some evidence that Alz not only is more likely to strike black and Hispanic people but also may progress differently. Researchers are looking for thousands of participants of these communities to participate in further research.
Half of older Americans fear that they’ll develop dementia-why most of their prevention methods are all wrong:
Nearly half of Americans in their 50s and early 60s fear that they’re likely to develop dementia as they age. However, only 5.2% of them have actually talked with a doctor about steps they could take to reduce the risk. Some people engage in strategies to help their memory that are not evidence-based. Policy and physicians should emphasize current evidence-based strategies of managing lifestyle and chronic medical conditions to reduce the risk of dementia. A recent study peer-reviewed by JAMA found that living a healthy lifestyle could help you reduce your risk of dementia. Those with high genetic risk and an unfavorable lifestyle were almost 3 times more likely to develop dementia vs those with low genetic risk and a favorable lifestyle. However, those with high genetic risk but still followed a healthy lifestyle were at a 32% lower risk.
Regaining strength, hope as a caregiver:
Informal caregivers often fill in gaps between medical professionals or paid aides to meet the needs of incapacitated individuals. Many caregivers view their services as a form of charitable giving. Others see it as simply being a good friend or family member. Although it can be rewarding to care for another person, caregiving also can be a stressful job that takes a physical and emotional toll. To remain as healthy as possible, caregivers should take steps to recognize symptoms of caregiver stress and avoid burnout. Here are some signs to keep in mind; Feelings of being overwhelmed; Feeling alone or deserted by others; Social withdrawal from friends or activities that used to make you feel good; Exhaustion that makes it challenging to complete necessary tasks; Sleeplessness or sleeping more than normal; Lack of concentration that influences daily tasks; Overreaction to minor nuisances; Cutting back on leisure activities; Neglecting things at home or other people who are well; or An immune system that is run down, leading to constant illness. If you start experiencing these symptoms it is important to take a step back from your caregiving and get help from others.
Rapid AI Enhanced Advanced Medical Imaging for Stroke Now Installed in Vietnam:
RAPID is a worldwide leader in advanced imaging for stroke, is now available and installed in Vietnam. Their artificial intelligence framework helps to qualify brain lesions and extend the window of potential stroke intervention from six hours after onset to up to 24 hours. They provide physicians with fast, fully automated, and easy to interpret imaging that facilitates clinical decision making around strokes. Strokes are a medical emergency and urgent treatment is essential to mitigate damage to brain tissue. However, only about 19% of patients arrive at hospitals within the crucial 4-6 hours. This technology helps increase the treatment window and aids the hospitals to address more cases with higher efficiency.